Keep the Foot

Neal Ryan Barshes,

MD, MPH

Vascular Surgery · Author · Educator

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As an academic vascular surgeon, I work to develop cost-effective, resilient, and equitable strategies to prevent leg amputations.

Tenets of Treatment

Pages providing practical guidance with rationale and evidence. Included here both for routine clinical care, and also with the hope that consistent, evidence-based management might help decrease the racial and ethnic disparities in leg amputation rates in Texas and elsewhere.

  1. Deep infections get drained/incised.
  2. Ensure or establish adequate arterial inflow.
  3. Reconstruct, reestablishing intact epithelium over the entire extremity.
  4. Maintain mobility – even if amputation is performed.

This is a summary of our current approach and evidence supporting it. An overview of the foot ulcer-limb loss disease process is in our “System of Care” review paper and our “framework” review paper. summarizes clinical outcomes in patients with foot ulcers and peripheral artery disease.

Manuscripts

  1. Foot ulcer prevention clearly represents to best opportunity for cost savings: reduced amputation rates + lower cost than current care.
  2. All patients with large or infected foot ulcers merit objective testing (toe pressures, skin perfusion pressures, or angiogram) to identify peripheral artery disease. This diagram demonstrates the optimal diagnostic strategies for peripheral artery disease identification.
  3. Leg bypass operations have lower perioperative mortality than leg amputation in patients with advanced comorbidities.
  4. Providing revascularization and limb salvage efforts appears to be cost-effective for all patients and may even provide cost-savings in elderly, functionally-marginal patients.
  5. Foot infections in bone (osteomyelitis) with E. coli or Pseudomonas are associated with worse outcomes; infections with methicillin-sensitive Staphylococcus aureus.

For Texans Interested in Addressing the Disparities in Leg Amputation Rates

  1. This two-page health policy brief, written with the University of Texas Medical Branch’s Center to Eliminate Health Disparities, summarizes the problems caused by leg amputations and suggests some steps forward.
  2. Significant racial and ethnic disparities persist in Texas, as people categorized as Black and people categorized as Hispanic undergo higher risk-adjusted rates of leg amputations than people categorized as White.
  3. Geography and lack of nearby specialist care at high-volume centers may contribute to leg amputation rates in many areas of Texas in these areas of Texas.
  4. See maps demonstrating population-adjusted rates of peripheral artery disease-associated leg amputations within the largest four metropolitan areas in Texas. You can also peruse the interactive Texas state maps showing the annual incidence rate of leg amputations by county, the frequency of leg amputations among persons categorized as Hispanic by county, and the proportion of lower extremity revascularizations done as surgical bypasses (rather than endovascular interventions) by zip code.